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doi: 10.1093/jn/nxaa310 72
The highly reactive NAPQI metabolite binds covalently to cell macromolecules, leading to dysfunction of enzymatic systems and structural and metabolic disarray
Construction of the SEO1 promoterLacZ fusion constructs for the -galactosidase reporter assay The SEO1 promoter sequence (600bp) was PCR amplified using oligonucleotides listed in Table S2
One of the key pathogenic factors is the antioxidant system
