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Description
Although IGF2 gene expression is not under GH control, the circulating levels of IGF-II are largely influenced by GH status since IGF-II (as well as IGF-I and IGFBP-3) is rapidly cleared from the circulation if not bound in the ternary complex

[DOI] [PubMed] [Google Scholar] 282
Your deficiency is moderate to severe, causing significant symptoms like anemia or neurological problems

On the basis of CD and NMR studies: (i) the Cys2-Cys7 loop conformation has a short-span of helix (Ala5-Cys7)
