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Differential response of skeletal muscles to mTORC1 signaling during atrophy and hypertrophy

Along with this limitation, current approaches are labor intensive, highly dependent on expensive growth factors and not amenable to scaling

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Opposite to the cytoplasmic reductive shift in C57BL/6J brain with aging driven by decreased pyruvate levels, neurons isolated from a mixed C57BL/6 129 mouse background showed an oxidized total NADPH/NADP + with aging (Ghosh et al., 2014)
