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Comparison of BRD4 ChIP-seq data from various cancer cell lines and normal cells showed that BRD4 occupies the ASXL1 promoter in all datasets analyzed, with a particularly high level of BRD4 being observed in glioblastoma (Fig

It is a progressive disease and, if left untreated, may lead to liver disease, central nervous system dysfunction and death[2,3]

Funding This research was funded by the Natural Science Foundation of Guangdong Province (2019A1515011829, 2019A1515011702), the Guangdong Provincial Special Fund for Marine Economic Development Projects (Yue Natural Resources Contract No