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In this process, ( Figure 7C ) initial attack of the lipid peroxide radical with a sugar molecule, followed by reaction with molecular oxygen forms a sugar peroxyl radical
H.SwansonP.ClarkeW.PlisetskayaE.DickhoffW.MoriyamaS.et al (2000)
The deletion or inactivation of Parkin down-regulates PGC-1, which in turn leads to the selective degeneration of dopamine neurons in the substantia nigra pars compacta (SNpc)
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