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Description
Nature, v

In primary biliary cholangitis (PBC), PD-1-targeted CAR-T cells deplete CD4 T cells, reducing biliary epithelial cytotoxicity in mice (85)

295 Consistently, AGK2, a SIRT2-specific inhibitor, promotes the therapeutic effects of ES by inducing the lactylation of METTL16-mediated cuproptosis in gastric tumors in vitro and in vivo

Even with excellent clinical trial safety data, individual responses may vary
