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Microglia-mediated neurotoxicity: uncovering the molecular mechanisms

Data from a cross-sectional study showed a positive relationship between bone mineral density and -tocopherol level in elderly Chinese population (Shi et al., 2016)

Subsequently, nucleus translocation of PARP1-dependent AIF interacts with macrophage migration inhibitory factor (MIF) to format the AIF-MIF complex, which further induces the DNA breakage and ultimately results in parthanatos [140]