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This complex represents a key step in excluding proteins from the apical domain, which promotes the polarity distribution of proteins between apical, lateral and basement membranes via regulating cytoskeleton 27,28,29

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doi: 10.1056/nejm199108013250501 [DOI] [PubMed] [Google Scholar] 254.Yusuf S, Pitt B, Davis CE, Hood WB Jr., Cohn JN

And because the higher dose (over 12 mg a day) can have some mild side effects such as a mild redness of the skin
