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SGLT2 inhibitors in patients with heart failure with reduced ejection fraction: a meta-analysis of the EMPEROR-Reduced and DAPA-HF trials

Reduces Inflammation & Oxidative Stress Chronic inflammation contributes to nerve damage
METex14 mutations are detected most frequently in NSCLC [51,52,53]

As of 2024, the MHRA (Medicines and Healthcare products Regulatory Agency) has authorised Mounjaro for use in adults with obesity (BMI 30) or overweight (BMI 27) with at least one weight-related comorbidity, such as hypertension, dyslipidaemia, or obstructive sleep apnoea
