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doi: 10.1101/gad.314617.118 161 ValentiRHuberVFilipazziPPillaLSovenaGVillaAet al

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The presence of the D1236 (from MRP2 substitution) instead of G1228 (wild-type MRP1) in the chimera M8 could create a steric hindrance, as shown by the Cryo-EM apo and LTC 4 bound (inward-facing) structures of bovine MRP1 40,44 (Fig

The groups message to President Trump specifically referenced his earlier pledge to cut drug prices by eliminating middlemen, encouraging him to build on prior momentum