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These observations suggest that glutathione induces aerobic metabolism and improves an acidic environment in skeletal muscle during exercise by elevating PGC-1, which would prevent exercise-induced fatigue

Pretreatment with schisantherin A provided neuroprotection against induced cytotoxicity, regulated the intracellular accumulation of reactive oxygen species and inhibited NO overproduction by reducing the overexpression of inducible nitric oxide synthase in cells [206]