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In one study, 17 CRC cases with MSI were screened for somatic mutations, resulting in one out of seven MLH1-D tumors with two somatic mutations in MLH1 and three out of eight MSH2-D tumors with two somatic mutations in MSH2 [58]

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In contrast to folate deficiency, the small folate cycle can run almost as normal

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Relative contributions of cystathionine beta-synthase and gamma-cystathionase to H 2 S biogenesis via alternative trans-sulfuration reactions

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1992;15(9 Suppl 6):1217

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