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After exposure to oxidative stimuli, Nrf2 dissociates from Keap1, its negative regulator, and translocates into the nucleus where it heterodimerizes with small Maf proteins [77] and binds to antioxidant responsive element (ARE) sequences, triggering a cytoprotective adaptative response

Previous cell and animal studies [115,116,117,118,119,120] have indicated that certain plant food components (e.g., glucosinolate metabolites and dithiothiones in brassica vegetables

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