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Description
Limited case series have suggested the therapeutic effect of sildenafil on HAPE
Unlike exogenous antioxidants derived from fruits and vegetables, glutathione is synthesized in liver cells
Human data are limited and mixed: Clinical studies have largely assessed safety and metabolism, while weight-related outcomes were modest and inconsistent
This large diversity is thought to be unique among classes of small molecule endobiotics, however, the evolutionary forces driving the variation remain poorly understood
