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However, although the challenge inoculum was the same as in the first study, areas of diffuse alveolar damage were detected in six out of eight vaccinated macaques compared with one out of eight control animals euthanized at 7 days, as well as at 35 days
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E.IsolauriE.et al
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The pharmacokinetic rationale is questionable given tirzepatide 5-day half-life
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