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Description
This can stimulate inflammatory pathways, leading to the phosphorylation of the IkappaB alpha protein and the production of inflammatory cytokines (35)

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Brestoff JR, Singh KK, Aquilano K, Becker LB, Berridge MV, Boilard E, Caicedo A, Crewe C, Enrquez JA, Gao J, et al

Novel derivatives of anaplastic lymphoma kinase inhibitors: synthesis, radiolabeling and preliminary biological studies on crizotinib and alectinib analogues
