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Another study of Raghunath et al

N 1 -acetylspermine and N 1 -acetylspermidine are converted to spermidine and putrescine, respectively, by polyamine oxidase (encoded by the PAOX gene) along with the production of H 2 O 2 and 3-acetylaminopropanal (3Ac-AP or 3-AAP)

Tumor spheroid formation assay K1 thyroid cancer cells (1 10 4 ) were seeded into a 96-well ultra-low-binding plate in organoid-specific media

Proc Natl Acad Sci U S A 101: 20402045, 2004 [DOI] [PMC free article] [PubMed] [Google Scholar] 171.Wakabayashi N, Itoh K, Wakabayashi J, Motohashi H, Noda S, Takahashi S, Imakado S, Kotsuji T, Otsuka F, Roop DR, Harada T, Engel JD, and Yamamoto M