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Short polar amino acid substituents also improved the binding (compound 41 and 42 , Figure S5), whereas affinity was lost with lysine substitution

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do not freeze the mixed solution, as freezing can denature peptides [7]

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Research teams have observed this peptide to bind to the ghrelin or growth hormone secretagogue 1a receptors (GHS-R1a), which are present in the hypothalamus and the pituitary gland

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Francis G, Baillie J

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