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Description
Mitochondrial respiration is crucial for cellular function, but it is also an endogenous source of ROS
Ferroptosis can therefore be induced by depriving cells of the sulfur-containing GSH precursor, cysteine, via inhibition of the system x c cystine/glutamate antiporter (e.g., using small molecules of the erastin family), or by direct inhibition of GPX4 itself (Forcina & Dixon, 2019)
Nanoparticle Targeted Drug Delivery to the Lungs Using Extra-Testicular Sertoli Cells
Fitoterapia 83 (7), 11601168
