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Tanshinone IIA and berberine can displace warfarin from human serum albumin (HSA), increasing free warfarin levels and enhancing its anticoagulant effect

For CLSM examination, tumor cells were cultured in a 12-well plate containing glass coverslips and subjected to staining with CRT antibodies, fluorescence-labeled secondary antibodies, and DAPI

Next, the occurrence of ferroptosis is due to the production of ROS by excessive free Fe 2+ under the action of Fenton reaction, which produce lipid peroxidation caused by oxidized lipids

This caused a long-lasting controversy whether APAP-induced cell death is caused by protein adduct formation or by oxidant stress-derived LPO