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Cell 77 IshigakiA.AokiM.NagaiM.WaritaH.KatoS.KatoM.et al (2007)

Inadequate secretion of intrinsic factor, resulting from lesions that destroy the gastric mucosa (ingestion of corrosives, extensive neoplasia), and a number of conditions associated with a variable degree of gastric atrophy (such as multiple sclerosis, certain endocrine disorders, iron deficiency, and subtotal gastrectomy)

Chen F, Zhang H, Zhan Y, Huang X, He Z, Ma D, et al

For spinal structures with naturally limited blood supply (particularly the intervertebral discs, which are largely avascular), this enhanced circulation to surrounding tissues can make a meaningful difference in healing capacity