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doi: 10.1186/s12872-024-04046-z

What it does not yet have is a controlled human trial

MSC-EVs function predominantly by the activation of autophagy via the catalase enzyme, the Nrf2 signalling pathway, the miR 146a-inhibited NF-B pathway, and the targeting of the PTEN-PI3 K/Akt pathway by miR-223 (145)
Abstract Epidemiologic studies detected an inverse relationship between HDL-C levels and atherosclerotic cardiovascular disease (ASCVD) identifying HDL-C as a major risk factor for ASCVD and suggesting atheroprotective functions of HDL
