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When thermal stress is eliminated by raising D2 knockout animals to be raised in an environment at 30C, they develop obesity, glucose intolerance, and hepatic steatosis that is the result of impaired BAT T 3 -induced thermogenesis (36)

Volpato S, Bianchi L, Cherubini A, Landi F, Maggio M, Savino E, Bandinelli S, Ceda GP, Guralnik JM, Zuliani G, et al

cells were treated for different times and at different permeabilizer concentrations, during batch cell growth
