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reported that lipid peroxidation product 4-HNE inhibited pyroptosis and inflammasome activation of LPS stimulated macrophages (M1 macrophage) by directly disrupting the binding of NIMA-related kinases 7 to NLR Family Pyrin Domain Containing 3 (NLRP3) ( Different cytokines secreted by macrophages also have distinct effects on lipid peroxidation

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Moderate Aerobic Exercise Training Ameliorates Impairment of Mitochondrial Function and Dynamics in Skeletal Muscle of High-fat Diet-induced Obese Mice