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Low intracellular zinc induces DNA damage in cells via a combination of increased oxidative DNA damage and disruption of zinc-dependent proteins involved in DNA-repair pathways, leading to impaired DNA repair and altered expression of DNA damage response genes, resulting in DNA strand breaks and genome instability (Ho and Ames, 2002
By activating GLP-1 receptors in the brain, semaglutide GLP-1 enhances the feeling of fullness after meals, making it easier to control hunger and reduce overall calorie consumption
doi: 10.1038/s41598-022-10865-x 88 ShouJ
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