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Gastrointestinal health: A 2024 review notes that, though further research is necessary, clinical studies have found supplementation beneficial for managing leaky gut syndrome and improving intestinal permeability in conditions such as Crohns disease and irritable bowel syndrome (IBS)

a high-carbohydrate diet (HCD) despite short-term effects in favor of LCD (i.e., after 48 hours) [32]

Silymarin scavenges reactive oxygen species (ROS) and increases the activity of endogenous antioxidant enzymes, such as superoxide dismutase (SOD) and glutathione peroxidase, thereby mitigating oxidative damage in liver cells

Relying on this, tumor-bearing mice with weight loss showed lower GSH levels and higher GSH disulfide/GSH ratios [139]