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Antiretroviral HIV medications also deplete valuable L-carnitine, contributing to peripheral neuropathy

Mild swelling, redness, or tenderness may occur, but these usually disappear after a few days

While radiation induces ROS production that has a key role in induction of DNA double-strand breaks and activation of apoptosis signaling pathways, recent studies have shown that treatment with L-carnitine and its derivatives as potent antioxidants can inhibit DNA damage and activate DNA-repair genes through ROS reduction (65)

The authors also acknowledge the Gujarat Biotechnology Research Centre (GBRC), Ahmedabad, for providing access to the LC-MS/MS facility and technical support for metabolomic analysis
