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Overall, children diagnosed with ASD and positive family history had higher serum melatonin and nitric oxide levels, with significantly lower malondialdehyde/melatonin ratios, suggesting greater impaired oxidant-antioxidant metabolism and balance in children with ASD [117]


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It decreases VLDL synthesis and secretion by a) reducing hepatic lipogenesis (synthesis of FA from acetyl CoA), b) increasing beta-oxidation of FA and c) inhibiting TG-synthesizing enzymes (e.g., DGAT)
