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Description
doi: 10.1093/ajcn/nqaa434

Early programmes, institutional studies, and preclinical model work examined how the compound class might influence receptor signalling, cellular adaptation, or tissue-level response patterns under controlled conditions

However, contrary to the tumor-promoting potential of many angiogenic agents, BPC-157 has been shown to inhibit uncontrolled cell proliferation, downregulate VEGF expression, and counteract VEGF-driven tumorigenesis, including suppression of Ki-67 and VEGF pathway activation [31, 73]

Phase 2 dominates growth : Phase 2 trials jumped significantly from 1,711 (2024) to 2,278 (2025), the highest level ever seenmaking Phase 2 the primary growth engine
