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Global epidemiology of HCV subtypes and resistance-associated substitutions evaluated by sequencing-based subtype analyses

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This l-carnitine buffering effect also extends to the potentially toxic acyl-groups, resulting either from poorly metabolized fatty acyls and from xenobiotics such as antibiotics conjugated with pivalic acid and valproate [44], or from inhibition of certain metabolic pathways for example propionic acid in propionic acidemia [45]

He also added 50 years for the development of ceramics in his extension area because he figured the region was a backwater and it would take about that long for ceramics and other cultural artifacts to reach the area