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Calculate the percentage of glutathione (C 10 H 17 N 3 O 6 S) in the portion of Glutathione taken: Result = [(V B) N F 100]/W V = = titrant volume of the Sample (mL) B = = titrant volume of the Blank (mL) N = = titrant normality (mEq/mL) F = = equivalency factor, 307.32 mg/mEq W = = weight of the Sample (mg) Acceptance criteria: 98.0%101.0% on the dried basis IMPURITIES Inorganic Impurities Ammonium Standard solution: 10 g of ammonium from a diluted ammonium chloride solution Sample solution: 50 mg of Glutathione Analysis: Transfer the Sample solution and the Standard solution to separate 25-mL jars fitted with caps, and dissolve in 1 mL of water

Data 46 , 671674 (2001)

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For more information, please see the FDA webpage Skin Products Containing Mercury and/or Hydroquinone