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however, its high cost limits its accessibility ( Beyond treatment strategies, significant prevention efforts have been focused heavily on vector control, with long-lasting insecticide-treated nets (LLINs) proving effective in reducing transmission rates in endemic areas ( While visceral leishmaniasis has been the focus of extensive clinical trials, parallel efforts are advancing treatment strategies for cutaneous leishmaniasis (CL), where pentavalent antimonials remain a frontline choice despite concerns around toxicity and variable efficacy across different regions

A personalised strategy integrating senolytics with traditional therapies may provide optimal benefits for healthy aging and longevity while mitigating risks.38 Table 1 below compares senolytics and traditional methods targeting cellular senescence

In assessing lipogenesis, we found there was significant upregulation of genes involving FA and TG synthesis in low B12 not only in adipocytes from obese phenotype but also in adipocytes from lean subjects

One group served as an unvaccinated control