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Fredholm BB, IJzerman AP, Jacobson KA, Klotz K-N, Linden J (2001) International Union of Pharmacology

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J Womens Health (Larchmt)

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These observations led to studies to test the hypothesis that high-antioxidant diets given to 12-yr-old beagle dogs for 3 yr would lead to decreased OS in brain of 15-yr-old dogs that was associated with decreased AD-like neuropathology and improved cognition

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The cyclic peptide scaffold provides considerably enhanced enzymatic stability relative to linear -MSH analogues in biological assay media

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