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Simultaneously, the activity of ACAT is elevated, resulting in an overproduction of CE that accumulate in the endoplasmic reticulum

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Liu Y, Huang Z, Liu H, Ji Z, Arora A, Cai D, et al

Most promoter CpG islands (usually unmethylated) escape from de novo methylation during all developmental stages, and the activity of promoters with intermediate to high CpG content was negatively correlated with their DNA methylation status (Weber et al., 2007)
