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Those on the HFD received daily gavage administration of CB-839 (200 mg kg 1 body weight) or vehicle for 19 days (25% (w/v) hydroxypropyl--cyclodextrin (ThermoFisher) in 10 mmol l 1 citrate buffer (pH 2)), while the standard chow group received vehicle only
A lot more work has to be done in order to develop a comprehensive safety profile for this peptide
Mol Med Rep 12(1):389393
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