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To examine whether PPARa modulates neuronal ferroptosis through FSP1, we divided the mice into three groups: Mock, Lv -PPARa (PPARa over-expression) and Lv -PPARa + icFSP1 (PPARa over-expression with FSP1 inhibition) (Fig S3a)
10.1016/j.freeradbiomed.2012.06.025 Free
Picking up a fight: fine tuning mitochondrial innate immune defenses against RNA viruses

doi: 10.1200/JCO.1993.11.3.538