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Articles published prior to 2000 were not included, nor were non-human studies (such as animal or in vitro models), case reports, reviews, editorials, commentaries, or conference abstracts with incomplete data, studies with no renal outcomes or with insufficient data for extraction, duplicate publications, or studies with overlapping data

All flavonoids share this diphenylpropane (C6C3C6) backbone, although their chemical properties and activities vary depending on their specific structures and the spatial arrangement of functional groups (Shahidi and Ambigaipalan 2015)

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Calcium also controls the rate of cell division in the epidermis
