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In the absence of stress or pathway alteration, NRF2 protein levels are kept low by the Kelch-like-ECH-associated-protein 1 (KEAP1) and cullin3 (CUL-3) protein complex (Fig
Sleep deprivation undermines your immune system and contributes to chronic stress syndrome that leads to metabolic disorders
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doi: 10.1152/ajpgi.1992.263.5.G617
