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Description
Given the prevalence of anxiety and depression in these patients, which ranges from 13 to 80% [118], antidepressants and antiepileptic drugs, which have been shown to be effective in the majority of patients, could also have a positive effect on pain symptoms and could be an indication for pharmacological treatment at the first approach

PLoS ONE 6 , e19059 (2011)

It assists in detecting uncommon issues and facilitating secure utilization

Katz A Preprint: PSYARXIV
