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Interestingly, two patients reported a silent mutation in the GLRX5 gene, that results in non-syndromic microcytic congenital sideroblastic anaemia (cSA) [115,117] a condition that is associated with iron overload in mitochondria together with relative iron depletion in cytosol

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For instance, in diabetic rat models, AST significantly enhanced cognitive function by activating the PI3K/Akt signaling pathway, thereby reducing oxidative stress and neuroinflammation [106]

10.1016/j.ejps.2021.105747 CrossRef Google Scholar View reference in article 94 RahmanM