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It should be noted that in our study, there was an acute change in TMAO to reflect the cycling of TMAO concentration within the blood, whereas in other studies, more long-term treatment of TMAO has been used

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Although postoperative increases in testosterone levels and IIEF scores have been reported in some series, these studies are frequently uncontrolled or non-randomized, and the observed benefits may reflect regression to the mean, placebo effects, improved endocrine milieu, reduced pain burden, or psychological reassurance after treatment rather than direct reversal of a specific immune-inflammatory penile lesion

MarosiKKimSWMoehlKScheibye-KnudsenMChengACutlerRet al