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Description
We wondered whether CSOP could be used to determine the approximate location of antibody epitopes on multi-domain proteins by measuring the antibody height and comparing it to protein height
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When cellular cholesterol levels are decreased the transcription factor SREBP is transported from the endoplasmic reticulum to the Golgi where proteases cleave and activate SREBP, which then migrates to the nucleus and stimulates the expression of LDL receptors (Figure 4)
