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In rats, at least some of the behavioral effects of 5-HTP are due to increased levels or turnover of 5-HTP in peripheral serotonergic neuronal systems [105] and 5-HTP neurotoxicity caused by brainblood barrier breakdown, edema formation, and NO production was found to be instrumental in causing adverse mental and behavioral abnormalities [106]

BMC Gastroenterology , 17(1), 96

PMID: 86 YanoJMYuKDonaldsonGPShastriGGAnnPMaLet al

[DOI] [PubMed] [Google Scholar] 29.Heidari F., Afshari M., Moosazadeh M