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The integrity of the endothelium and oxidative damage could be restored and reversed respectively, which was linked to the increased expression and internalisation of VEGFR2

To assess the protective function of Protandim on OPC maturation under the inhibitory influence of inflammation or oxidative stress, OPCs were synchronized by growth factors for 2 days and subsequently treated with 30 g/mL of Protandim or EtOH, as vehicle control
