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It also reduces vascular remodelling and stiffness and improves arterial flexibility by suppressing vascular smooth muscle cell migration and proliferation as well as TGF--mediated fibrosis

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10.1016/j.clinthera.2020.09.008 302

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IGF1R upregulation confers resistance to isoform-specific inhibitors of PI3K in PIK3CA-driven ovarian cancer

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Commun Biol 7(1):428

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