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Atherosclerosis: TMAO Activates ERS The ER, formed in continuity with the outer membrane of the nuclear envelope, plays a key role as a central eukaryotic membranous organelle and is responsible for the synthesis, folding, and maturation of membrane and secreted proteins, lipid biosynthesis, and calcium storage (67)

have shown that acceptance interventions are effective in reducing kinesiophobia and improving performance-related physical functioning in individuals with comorbid obesity, as they can facilitate adherence to physical activity and promote weight loss in this highly comorbid clinical condition [102]

Carnitine deficiency seen in liver disease may cause metabolic dysfunctions in gluconeogenesis, fatty acid metabolism, albumin biosynthesis, and ammonia detoxification by the urea cycle [71]

Tk I, Starcuk Z, Choi IY, Gruetter R