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While coffee is still the most widely consumed source of caffeine, caffeinated energy drinks have become increasingly popular

In another small study involving 15 patients receiving hemodialysis (where blood is pumped out of the body to an artificial kidney machine), they were found to have gastrointestinal symptoms, including constipation (likely due to restrictions in their water intake required as part of their therapy), as well as carnitine deficiency

Researchers prefer to study acetyl-L-carnitine because it is better absorbed in the small intestine than other forms, and more efficiently crosses the blood-brain barrier

Liver-derived acylcarnitine can serve as an energy substrate, particularly during prolonged exercise or fasting