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The upregulation and activation of 7nAChR subsequently activate several signaling pathways, including neuroprotective PI3K/Akt and Nrf2 pathways, then suppression of pro-apoptotic caspase-3, and suppression of NF-B that reduce the expression of proinflammatory cytokines such as IL-1, and TNF- [50, 86]

Performing in silico PCR, we were able to assess whether regions analyzed were in the same genomic position and discuss the results accordingly

The studies concluded that mitigating the higher order aggregates and particulates, decreased immune responses in the rodents tested 18, 19

[DOI] [PubMed] [Google Scholar] 41.Rabin N., Zheng Y., Opoku-Temeng C., Du Y., Bonsu E., Sintim H.O