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PMID 8532024

Tesamorelin is a synthetic GHRH analog: it copies growth hormone-releasing hormone and tells the pituitary gland to make more GH

Accumulation of ROS within the mitochondrial matrix can impair oxidative phosphorylation efficiency, leading to decreased ATP production and opening of the mitochondrial permeability transition pore (mPTP) (Zorov et al., 2014

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