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Research shows that taking B12 in a sublingual oral form is more effective for treating B12 deficiencies than actually getting B12 intramuscular shots (and it's usually much more convenient and affordable as well)

Methotrexate (MTX), another commonly used chemotherapy, impacts the integrity of TJs in the intestine

Journal of Applied Physiology, 110(3), 774-780

Its a substrate and a cofactor, meaning it gets used up doing chemical reactions and then regenerated

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